Unlocking Cures For Pediatric Cancer With Artificial Intelligence

Pediatric cancer is the leading disease-related cause of death among Americans ages 1–19. The initiative aims to accelerate discoveries and clinical trials while protecting patient privacy and control over health information.

What the order does ​

• Directs the Make America Healthy Again Commission and federal health and technology officials to develop AI-driven approaches to pediatric cancer.
• Expands the Childhood Cancer Data Initiative’s AI-ready data platforms, research tools, and support for projects at National Cancer Institute-Designated Cancer Centers.
• Prioritizes AI tools for predicting treatment response, disease progression, toxicity, biomarkers, and clinical trial eligibility.
• Seeks to improve clinical trial design, access, recruitment, administration, and interpretation using multimodal data and AI.
• Directs officials to identify more existing federal funding for pediatric cancer initiatives and encourage private-sector investment in advanced technologies.
• Requires work toward interoperable standards that allow health records and claims data to support AI research while preserving privacy and patient or parent control.

Who it affects ​

• Children, adolescents, and young adults with cancer and their families.
• Pediatric cancer researchers, clinicians, clinical trial participants, and National Cancer Institute-Designated Cancer Centers.
• Healthcare, academic, and technology organizations using patient data and AI for research or care.